Calorie restriction: what recent results suggest for the future of ageing research

Calorie restriction as an intervention in ageing

Ageing causes loss of function in tissues and organs, is accompanied by a chronic inflammatory process and affects life- and healthspan. Calorie restriction (CR) is a non-genetic intervention that prevents age-associated diseases and extends longevity in most of the animal models studied so far. CR produces a pleiotropic effect and improves multiple metabolic pathways, generating benefits to th...

Update on human calorie restriction research.

The United States population is aging rapidly, and understanding the potential impact and feasibility of lifestyle interventions on the aging process is of central importance for addressing future population health and health care costs. This symposium addressed the question of whether caloric restriction may be a feasible strategy to improve human health by reductions in rates of primary and s...

Calorie Restriction, Longevity and Cognitive Function

Calorie Restriction

Calorie restriction, or caloric restriction (CR), is a dietary regimen thought to improve health and slow the aging process in some animals and fungi by limiting dietary energy intake below the average needs. CR is the only dietary intervention which has been documented to increase both the median and maximum lifespan in a variety of species, among them rodents, yeast, fishes and dogs. The life...

The Future of Ageing and Its Health Care Costs: A Warning for Health System

This article is focused on ageing and the rapid ageing population growth, from future health care costs prospectus. It reviews ageing population statistics in several courtiers as well as Iran, to illustrate the significance of the ageing population growth in the next decades. Nevertheless, the health care costs for elderly people are described and the considerable differences between health ca...